Investigator in Rome, Italy Will Examine the Role of the A-T Protein in Cellular Suicide A researcher in Italy will attempt to better understand the role of the A-T protein (ATM) in programmed cell death or suicide, a process that scientists call “apoptosis.” Knowledge of how ATM regulates apoptosis will provide insight into the pathology of this disease and help researchers develop potential therapeutic interventions. more                    

Oxidative Stress in Patients with Ataxia-Telangiectasia
Funded by the A-T Children’s Project, Howard Lederman, MD, PhD, Director of the A-T Clinical Center at Johns Hopkins Hospital in Baltimore, Maryland, will study how a combination of two dietary supplements, an antioxidant and a PARP-1 inhibitor can slow the neurodegeneration and aid the pulmonary problems seen in patients with A-T. more